Indication: Used for pain, fever, and inflammation in conditions like musculoskeletal pain, sore throat, or dental pain.
- Pain: A physical discomfort that may be sharp or throbbing, commonly due to tissue injury or illness.
- Fever: Elevated body temperature usually caused by infection or inflammation. It often leads to fatigue and discomfort.
- Inflammation: Redness, swelling, and warmth due to the body’s immune response to injury or infection.
MOA: Nimesulide is a selective COX-2 inhibitor that reduces inflammation and pain. Paracetamol acts centrally to lower fever and relieve pain by inhibiting prostaglandin synthesis in the brain.



